Recombinant MTDH antibody (AA 475-525)

Catalog No. ABIN7795651

This anti-MTDH antibody is a Rabbit Monoclonal antibody detecting MTDH in WB, IHC, FACS, IP and ICC. Suitable for Human and Mouse.

Quick Overview for Recombinant MTDH antibody (AA 475-525) (ABIN7795651)

Target: MTDH (Metadherin (MTDH))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MTDH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR258L

Product Details anti-MTDH Antibody

Binding Specificity: AA 475-525

Purpose: Rabbit anti-LYRIC/AEG1 Recombinant Monoclonal Antibody [BLR258L]

Purification: Purified

Immunogen: Between 475 and 525

Isotype: IgG

Application Details

Application Notes: Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,150 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,150 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,20 μL/mg lysate ,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 250 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for MTDH

Target: MTDH (Metadherin (MTDH))

Alternative Name: LYRIC/AEG1

Background: Astrocyte elevated gene-1 protein (AEG1) is also known as metadherin. AEG1 AEG1 promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. It also promotes lung metastasis and has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. AEG1 induces chemoresistance.

Gene ID: 92140

UniProt: Q86UE4

Pathways: Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization